Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of HbpR binding by site-directed mutagenesis of its DNA-binding site and by deletion of the effector domain.

The FEBS journal - 1 Apr 2005

Tropel David, van der Meer Jan R

Abstract excerpt

In the presence of 2-hydroxybiphenyl, the enhancer binding protein, HbpR, activates the sigma54-dependent P(hbpC) promoter and controls the initial steps of 2-hydroxybiphenyl degradation in Pseudomonas azelaica. In the activation process, an oligomeric HbpR complex of unknown subunit composition binds to an operator region containing two imperfect palindromic sequences. Here, the HbpR-DNA binding interactions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Binding Sites
Share to DNA Footprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Mutagenesis, Site-Directed

Share to Promoter Regions, Genetic

Share to Pseudomonas

Share to Trans-Activators

Source

Identifiers

PMID: 15794762
DOI: 10.1111/j.1742-4658.2005.04607.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of HbpR binding by site-directed mutagenesis of its DNA-binding site and by deletion of the effector domain.PMID 15794762Read ↗

Mutant HbpR transcription activator isolation for 2-chlorobiphenyl via green fluorescent protein-based flow cytometry and cell sorting.Semantic proximity Read ↗

HbpR, a new member of the XylR/DmpR subclass within the NtrC family of bacterial transcriptional activators, regulates expression of 2-hydroxybiphenyl metabolism in Pseudomonas azelaica HBP1.Semantic proximity Read ↗

Design of new promoters and of a dual-bioreporter based on cross-activation by the two regulatory proteins XylR and HbpR.Semantic proximity Read ↗

Mutation analysis of PobR and PcaU, closely related transcriptional activators in acinetobacter.Semantic proximity Read ↗

Functional analysis of the EspR binding sites upstream of espR in Mycobacterium tuberculosis.Semantic proximity Read ↗

HosA, a MarR Family Transcriptional Regulator, Represses Nonoxidative Hydroxyarylic Acid Decarboxylase Operon and Is Modulated by 4-Hydroxybenzoic Acid.Semantic proximity Read ↗

The role of the interdomain B linker in the activation of the XylR protein of Pseudomonas putida.Semantic proximity Read ↗

DNA binding of PhoB and its interaction with RNA polymerase.Semantic proximity Read ↗

Broadening the signal specificity of prokaryotic promoters by modifying cis-regulatory elements associated with a single transcription factor.Semantic proximity Read ↗

Role of the recognition helix of response regulator WalR from Bacillus anthracis in DNA binding and specificity.Semantic proximity Read ↗

Transcriptional control by two interacting regulatory proteins: identification of the PtxS binding site at PtxR.Semantic proximity Read ↗

Thermodynamic and molecular analysis of the AbrB-binding sites within the phyC-region of Bacillus amyloliquefaciens FZB45.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.