Article
High-level beta-lactam resistance associated with acquired multidrug resistance in Helicobacter pylori.
Antimicrobial agents and chemotherapy - 1 Jul 2003
Kwon Dong H, Dore M P, Kim J J, Kato M, Lee M, Wu J Y, Graham D Y
Abstract excerpt
Four clinical Helicobacter pylori isolates with high-level resistance to beta-lactams exhibited low- to moderate-level resistance to the structurally and functionally unrelated antibiotics ciprofloxacin, chloramphenicol, metronidazole, rifampin, and tetracycline. This pattern of multidrug resistance was transferable to susceptible H. pylori by natural transformation using naked genomic DNA from a clinical...
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