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Article

Molecular Mechanisms of β-Lactam Resistance and Its Contribution to Multidrug Resistance in Helicobacter pylori.

The Journal of infectious diseases - 13 Mar 2026

Zhou Jun, Tang Xiaoqiong, He Liqing, Zhang Fandi, Mou Xingyu, Zhao Ninglin, Li Hong, Bao Rui

Abstract excerpt

Helicobacter pylori is a significant pathogen associated with a range of diseases, most notably gastritis and gastric cancer, making it a critical target for medical intervention. β-lactam antibiotics, known for their potent bactericidal properties, play a central role in clinical regimens aimed at eradicating H pylori. However, the increasing resistance of H pylori to β-lactams, compounded by the rise of...

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PMID: 41824654
DOI: 10.1093/infdis/jiaf385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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