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Article

Transcriptional Regulation of Apolipoprotein A5 Gene Expression by the Nuclear Receptor RORα

25 Mar 2005

Abstract excerpt

OBJECTIVE: The newly identified apolipoprotein A5 (APOA5), selectively expressed in the liver, is a crucial determinant of plasma triglyceride levels. Because elevated plasma triglyceride concentrations constitute an independent risk factor for cardiovascular diseases, it is important to understand how the expression of this gene is regulated. In the present study, we identified the retinoic acid receptor-related...

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Identifiers

PMID: 15790933
DOI: 10.1161/01.atv.0000163841.85333.83

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