Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of aromatase expression by retinoic acid receptor-related orphan receptor (ROR) alpha in breast cancer cells: identification of a novel ROR response element.

The Journal of biological chemistry - 26 Jun 2009

Odawara Hiroki, Iwasaki Toshiharu, Horiguchi Jun, Rokutanda Nana, Hirooka Kazumi, Miyazaki Wataru, Koibuchi Yukio, Shimokawa Noriaki, Iino Yuichi, Takeyoshi Izumi, Koibuchi Noriyuki

Abstract excerpt

Estrogen is a key regulator of the proliferation and differentiation of breast cancer cells. In addition to the estrogen supply from the ovary, estrogen is produced locally from androgen by aromatase. However, the regulation of aromatase gene expression in breast cancer has not yet been fully clarified. Retinoic acid receptor-related orphan receptor (ROR) alpha plays an important role in the differentiation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Luciferases

Share to Nuclear Receptor Subfamily 1, Group F, Member 1

Share to Receptors, Cytoplasmic and Nuclear

Share to Response Elements

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 19439415
DOI: 10.1074/jbc.M109.009241
PMCID: PMC2719410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of aromatase expression by retinoic acid receptor-related orphan receptor (ROR) alpha in breast cancer cells: identification of a novel ROR response element.PMID 19439415Read ↗

Retinoic acid-related orphan receptor alpha (RORA) variants and risk of breast cancer.Semantic proximity Read ↗

Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.Semantic proximity Read ↗

Unraveling the physiological roles of retinoic acid receptor-related orphan receptor αSemantic proximity Read ↗

The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes.Semantic proximity Read ↗

Emerging functional roles of nuclear receptors in breast cancerSemantic proximity Read ↗

Orphan nuclear receptors in breast cancer pathogenesis and therapeutic responseSemantic proximity Read ↗

Retinoid-Related Orphan Receptors (RORs): Critical Roles in Development, Immunity, Circadian Rhythm, and Cellular MetabolismSemantic proximity Read ↗

Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and MetabolismSemantic proximity Read ↗

The gene encoding human retinoic acid-receptor-related orphan receptor α is a target for hypoxia-inducible factor 1Semantic proximity Read ↗

Identification of the human ApoAV gene as a novel RORalpha target gene.Semantic proximity Read ↗

Minireview: Nuclear Receptors and Breast CancerSemantic proximity Read ↗

The role of retinoic acid receptor-related orphan receptors in skeletal diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.