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Article

Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling

1 Jan 2005

Abstract excerpt

Bone morphogenetic protein (BMP)-2 induces Osterix (Osx) in mouse C2C12 cells and chondrocytes. Genetic studies place Osx downstream to the BMP-2/Smad/Runx2 signaling pathway; however, limited information is available on the mediators of Osx expression in osteoblast lineage commitment. Several lines of research implicate the presence of Runx2-independent ossification. Therefore, the purpose of this study was to...

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PMID: 15786511
DOI: 10.1002/jcb.20429

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Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signalingPMID 15786511Read ↗

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