Article
Performance in the Wisconsin Card Sorting Test and the C957T polymorphism of the DRD2 gene in healthy volunteers.
Neuropsychobiology - 1 Jan 2006
Rodriguez-Jimenez R, Hoenicka J, Jimenez-Arriero M A, Ponce G, Bagney A, Aragues M, Palomo T
Abstract excerpt
INTRODUCTION: Previous studies have associated a decreased striatal D2 dopamine receptor (DRD2) binding with impaired performance in cognitive tasks. In vivo studies have found a lower DRD2 binding associated with the CC genotype of the C957T single nucleotide polymorphism (SNP) of the DRD2 gene. OBJECTIVE: The aim of this study was to investigate the relationship between executive functions and the C957T DRD2...
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