Article
Lack of association between common polymorphisms in genes of the renin-angiotensin system and mortality after myocardial infarction.
Cardiology - 1 Jan 2005
Andrikopoulos George K, Tzeis Stylianos M, Needham Edward W, Richter Dimitri J, Zairis Michalis N, Gialafos Elias J, Kardaras Fotios G, Foussas Stefanos G, Stefanadis Christodoulos I, Toutouzas Pavlos K, Mattu Raj
Abstract excerpt
The insertion/deletion (I/D) polymorphism in the ACE gene and the A1166C polymorphism in the AT1R gene have been associated with left ventricular remodelling and prognosis after acute myocardial infarction (AMI). We investigated whether these genetic variants associate with impaired left ventricular ejection fraction (LVEF) and increased risk for in-hospital mortality after AMI. Consecutive AMI patients were...
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