Article
Association of single nucleotide polymorphisms in GATA-3 with allergic rhinitis.
Acta oto-laryngologica - 1 Feb 2009
Zhang Luo, Wang Xiangdong, Han Demin, Duan Hong, Zhao Yan
Abstract excerpt
CONCLUSION: The results of our study demonstrated the association between the single nucleotide polymorphisms (SNPs) of GATA-3 and allergic rhinitis (AR). OBJECTIVE: AR is considered to be controlled by T-helper type 2 (Th2) cells. GATA-3 is the crucial transcription factor controlling the differentiation and function of Th2 cells. We aimed to evaluate the association between the SNPs of GATA-3 and AR. SUBJECTS...
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