The nk model and population genetics.

Abstract excerpt

The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis. To examine these claims, an infinite-allele approximation is introduced. In this limit, it is shown that the nk model is, at an appropriate level of description,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Epistasis, Genetic
• Share to Evolution, Molecular