Article
Variation in the FcgammaR3B gene among distinct Brazilian populations.
Tissue antigens - 1 Feb 2005
Covas D T, Kashima S, Guerreiro J F, dos Santos S E B, Zago M A
Abstract excerpt
The FCGR3B gene codes for the FcgammaR3b receptor, which occurs in three polymorphic forms representing the human neutrophil antigens (HNA)-1a, HNA-1b, and HNA-1c. The alleles that code for these antigens are FCGR3B*1, FCGR3B*2, and FCGR3B*3, respectively. New variants of these alleles have been recently described. In order to study the frequency of these alleles and the occurrence of variant forms, we sequenced...
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