Article
CDH1 associated gastric cancer: a report of a family and review of the literature.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Apr 2005
Moran C J, Joyce M, McAnena O J
Abstract excerpt
AIMS: Hereditary diffuse gastric cancer (HDGC) is an autosomal-dominant inherited form of gastric cancer associated with inactivating germline mutations in the CDH1 gene. We set out to outline the role of CDH1 in HDGC. Investigation of a family suspected as having HDGC is discussed. The role of s...
Topics
- Cadherins
- Female
- Gastrectomy
- Genetic Counseling
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Humans
- Male
- Population Surveillance
- Stomach Neoplasms
