Article
Identification of a novel splice variant of human PD-L1 mRNA encoding an isoform-lacking Igv-like domain.
Acta pharmacologica Sinica - 1 Apr 2005
He Xian-hui, Xu Li-hui, Liu Yi
Abstract excerpt
AIM: To investigate the expression and regulation of PD-1 ligand 1 (PD-L1) in peripheral blood mononuclear cells (PBMC). METHODS: The cDNA encoding human PD-L1 precursor was cloned from the total RNA extracted from the resting and phorbol dibutyrate plus ionomycin- or phytohemagglutinin-activated PBMC, by reverse transcription polymerase chain reaction (RT-PCR), and independent clones were sequenced and analyzed....
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