Article
The function of a novel immunophenotype candidate molecule PD-1 in chronic lymphocytic leukemia.
Leukemia & lymphoma - 1 Jan 2015
Grzywnowicz Maciej, Karabon Lidia, Karczmarczyk Agnieszka, Zajac Malgorzata, Skorka Katarzyna, Zaleska Joanna, Wlasiuk Paulina, Chocholska Sylwia, Tomczak Waldemar, Bojarska-Junak Agnieszka, Dmoszynska Anna, Frydecka Irena, Giannopoulos Krzysztof
Abstract excerpt
Programmed death-1 (PD-1) is a negative receptor expressed on lymphocytes including malignant B cells in chronic lymphocytic leukemia (CLL). In this work, we found that patients with CLL had a higher expression of PD-1 transcript (PDCD1) than healthy volunteers (p < 0.0001). PDCD1 expression was...
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