Article
Studying the biological and technical sources of variation in telomere length of individual chromosomes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 May 2005
de Pauw E S D, Roelofs H, Zwinderman A, van Houwelingen J C, Fibbe W E, de Knijff P, Pearson P L, Tanke H J
Abstract excerpt
BACKGROUND: Consistent average length differences between species and chromosome arm differences within species indicate that telomere length is genetically determined. This seems to contradict an observed large variation in lengths of the same human telomere between metaphases of the same individual. We examined the extent to which the variation in the telomeres of the human X and Y chromosomes is heritable,...
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