Article
Bone mass effects of a BMP4 gene polymorphism in postmenopausal women.
Bone - 1 Mar 2005
Ramesh Babu L, Wilson S G, Dick I M, Islam F M A, Devine A, Prince R L
Abstract excerpt
The pathogenesis of osteoporosis involves both genetic and environmental factors. On the basis of linkage data suggesting gene effects on bone density at chromosome 14q and data locating the BMP4 gene to 14q, we performed a positional candidate study to examine a possible association of BMP4 gene polymorphisms, hip bone density (n = 1012) and fracture rates (n = 1232) in postmenopausal women (mean age 75). On...
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