Article
Genetic analysis of meningococci carried by children and young adults.
The Journal of infectious diseases - 15 Apr 2005
Claus Heike, Maiden Martin C J, Wilson Daniel J, McCarthy Noel D, Jolley Keith A, Urwin Rachel, Hessler Frank, Frosch Matthias, Vogel Ulrich
Abstract excerpt
BACKGROUND: Neisseria meningitidis is a diverse commensal bacterium that occasionally causes severe invasive disease. The relationship between meningococcal genotype and capsular polysaccharide, the principal virulence factor and vaccine component, was investigated in carried meningococci isolated from 8000 children and young adults in Bavaria, Germany. METHODS: Of the 830 meningococci isolated (carriage rate,...
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