Article
Genotypic and phenotypic comparison of Neisseria meningitidis carriage and invasive disease isolates contemporaneously collected in the Netherlands.
FEMS microbiology letters - 7 Jan 2026
Jones Charles H, Li Zhenghui, Hao Li, van der Ende Arie, Liberator Paul A, Anderson Annaliesa S, Murthy Ashlesh K
Abstract excerpt
Neisseria meningitidis (Nm), a commensal that colonizes the nasopharynx of 4.5%-24% of healthy humans, can cause invasive meningococcal disease (IMD). We hypothesized that distinct genotypic and/or phenotypic signatures might be found in carriage vs. invasive isolates. Carriage isolates were cultured from nasopharyngeal swabs (n = 267) collected from healthy students (aged 13-21 years) during the 2013 and 2014...
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