Increased genetic diversity of Neisseria meningitidis isolates after the introduction of meningococcal serogroup C polysaccharide conjugate vaccines.

doi:10.1128/JCM.43.9.4649-4653.2005

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Article

Increased genetic diversity of Neisseria meningitidis isolates after the introduction of meningococcal serogroup C polysaccharide conjugate vaccines.

Journal of clinical microbiology - 1 Sept 2005

Diggle Mathew A, Clarke Stuart C

Abstract excerpt

During the 1990s, the incidence of meningococcal disease was high in the United Kingdom. This was due primarily to an increase in serogroup C disease, particularly that within the ET-37/ST-11 genetic lineage. Serogroup C meningococcal polysaccharide conjugate vaccines were introduced in the United Kingdom in 1999, but the sequence types of meningococci causing disease since that time have not yet been reported....

Topics

Genetic Variation
Humans
Meningococcal Infections
Meningococcal Vaccines
Neisseria meningitidis
Polysaccharides
United Kingdom

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Identifiers

PMID: 16145121
DOI: 10.1128/JCM.43.9.4649-4653.2005
PMCID: PMC1234051

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