Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study of detoxification genes in age related macular degeneration.

The British journal of ophthalmology - 1 Apr 2005

Esfandiary H, Chakravarthy U, Patterson C, Young I, Hughes A E

Abstract excerpt

BACKGROUND/AIMS: Age related macular degeneration (AMD) is a complex disorder leading to loss of central vision, and identification of risk factors associated with susceptibility to AMD has been a key objective for ophthalmic genetics research for almost a decade. This association study has examined genetic polymorphisms in 12 candidate genes as possible risk factors for predisposition to the development of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Air Pollutants
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Inactivation, Metabolic

Share to Linkage Disequilibrium

Share to Macular Degeneration

Share to Oxidative Stress

Source

Open in PubMed Open full text

Identifiers

PMID: 15774926
DOI: 10.1136/bjo.2004.047340
PMCID: PMC1772608

Genes

EPHX1
CAT
GPX1
NAT2
PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study of detoxification genes in age related macular degeneration.PMID 15774926Read ↗

Allelic interaction effects of DNA damage and repair genes on the predisposition to age-related cataract.Semantic proximity Read ↗

The ERCC6 gene and age-related macular degeneration.Semantic proximity Read ↗

Analysis of antioxidative factors related to AMD risk development in the polish patients.Semantic proximity Read ↗

DNA Methylation Is Associated with Altered Gene Expression in AMDSemantic proximity Read ↗

Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration.Semantic proximity Read ↗

The Role of Glutathione in Age-Related Macular Degeneration (AMD)Semantic proximity Read ↗

[Study on gene-gene, gene-environmental interactions of DNA repair genes related with age-related cataract].Semantic proximity Read ↗

Polymorphisms of DNA repair genes OGG1 and XPD and the risk of age-related cataract in Egyptians.Semantic proximity Read ↗

Gene-environment interactions in ocular diseases.Semantic proximity Read ↗

Alteration in antioxidant status in slow and fast alleles of EPHX1 gene polymorphisms among wood workers.Semantic proximity Read ↗

Association between polymorphism of the NQO1, NOS3 and NFE2L2 genes and AMD.Semantic proximity Read ↗

Superoxide dismutase gene polymorphisms in patients with age-related cataract.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.