Article
Superoxide dismutase gene polymorphisms in patients with age-related cataract.
Ophthalmic genetics - 1 Sept 2013
Celojevic Dragana, Nilsson Staffan, Behndig Anders, Tasa Gunnar, Juronen Erkki, Karlsson Jan-Olof, Zetterberg Henrik, Petersen Anne, Zetterberg Madeleine
Abstract excerpt
BACKGROUND: Functional polymorphisms in genes encoding antioxidant enzymes may result in reduced enzyme activity and increased levels of reactive oxygen species, such as superoxide radicals, which in turn may contribute to increased risk of age-related disorders. Copper-zinc superoxide dismutases, SOD-1 and SOD-3, and manganese superoxide dismutase, SOD-2, are enzymes involved in the protection against oxidative...
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