Article
Protein kinase casein kinase 2 holoenzyme produced ectopically in human cells can be exported to the external side of the cellular membrane.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 2005
Rodríguez Fernando, Allende Catherine C, Allende Jorge E
Abstract excerpt
Ectokinases can phosphorylate extracellular proteins and external domains of membrane proteins influencing cell adhesion, movement, and cellular interactions. An ectokinase with the properties of casein kinase 2 (CK2) has been previously described, but little is known about the structural characteristics that allow this enzyme to be exported from the cell. Transfection of human embryonic kidney-293 cells with...
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