Article
ICAM-2 confers a non-metastatic phenotype in neuroblastoma cells by interaction with α-actinin.
Oncogene - 19 Mar 2015
Feduska J M, Aller S G, Garcia P L, Cramer S L, Council L N, van Waardenburg R C A M, Yoon K J
Abstract excerpt
Progressive metastatic disease is a major cause of mortality for patients diagnosed with multiple types of solid tumors. One of the long-term goals of our laboratory is to identify molecular interactions that regulate metastasis, as a basis for developing agents that inhibit this process. Toward this goal, we recently demonstrated that intercellular adhesion molecule-2 (ICAM-2) converted neuroblastoma (NB) cells...
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