Article
Polymorphisms in cytokine genes do not predict progression to end-stage heart failure in children.
Cardiology in the young - 1 Oct 2002
Webber Steven A, Boyle Gerard J, Gribar Steven, Law Yuk, Bowman Pamela, Miller Susan A, Awad Mohammed R, Ahmed Mamun, Martell Joan, Zeevi Adriana
Abstract excerpt
UNLABELLED: A number of cytokines have been implicated in the pathophysiology of congestive heart failure. Genetic polymorphisms of several cytokine genes are known to result in altered gene expression, enabling us to characterize patients as "high" or "low" producers of specific cytokines. We speculate that the cytokine genotypes for a population of children who underwent heart transplantation for end-stage...
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