Article
Molecular characterization of alpha-thalassemia in the Dohuk region of Iraq.
Hemoglobin - 1 Jan 2009
Al-Allawi Nasir A S, Badi Ameer I A, Imanian Hasham, Nikzat Nooshin, Jubrael Jaladet M S, Najmabadi Hossein
Abstract excerpt
The molecular basis of alpha-thalassemia (alpha-thal) has been addressed by several studies from the eastern Mediterranean region, but not from Iraq. To address this issue, we studied 51 individuals with unexplained hypochromia and/or microcytosis, as well as nine patients with documented Hb H disease from the Dohuk region in northern Iraq. We used multiplex gap-polymerase chain reaction (gap-PCR), reverse...
Topics
- Anemia, Hypochromic
- DNA Mutational Analysis
- Genotype
- Humans
- Iraq
- alpha-Thalassemia