Article
The Hb H disease genotypes in Southern China.
Hemoglobin - 1 Jan 2014
Fang Jianpei, Chen Luming, Zeng Ruiping, Tian Qiuhong, Jiang Weiying, Li Hongyi, Chen Zheng, Du Chuanshu, Chen Suqin
Abstract excerpt
Abstract We report the genetic data of 435 patients with Hb H (β4) disease who presented at our center between 2005 and 2012. Our results showed that all patients had the Southeast Asian deletion (- -(SEA)) on one allele. The -α(3.7) (rightward) deletion was the most common on the other allele, followed by the -α(4.2) (leftward) deletion, Hb Constant Spring (Hb CS, α142, Term → Gln; HBA2: c.427T > C) and Hb...
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