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Article

MET Receptor Tyrosine Kinase Sequence Alterations in Differentiated Thyroid Carcinoma

14 Mar 2005

Abstract excerpt

Activating mutations affecting the MET receptor tyrosine kinase are present in several types of human cancer, particularly in papillary renal cell carcinoma. Papillary thyroid carcinomas commonly express high levels of MET mRNA and protein, suggesting that increased MET signaling may be of importance in the molecular pathogenesis of differentiated thyroid carcinoma. To evaluate the role of MET mutations in...

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Identifiers

PMID: 15767811
DOI: 10.1097/01.pas.0000156103.37756.e2

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