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Article

Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection.

American journal of human genetics - 1 Dec 2009

Rozen Steve, Marszalek Janet D, Alagappan Raaji K, Skaletsky Helen, Page David C

Abstract excerpt

Y-linked single-nucleotide polymorphisms (SNPs) have served as powerful tools for reconstructing the worldwide genealogy of human Y chromosomes and for illuminating patrilineal relationships among modern human populations. However, there has been no systematic, worldwide survey of sequence variation within the protein-coding genes of the Y chromosome. Here we report and analyze coding sequence variation among the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20004767
DOI: 10.1016/j.ajhg.2009.11.011
PMCID: PMC2790577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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