Article
Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection.
American journal of human genetics - 1 Dec 2009
Rozen Steve, Marszalek Janet D, Alagappan Raaji K, Skaletsky Helen, Page David C
Abstract excerpt
Y-linked single-nucleotide polymorphisms (SNPs) have served as powerful tools for reconstructing the worldwide genealogy of human Y chromosomes and for illuminating patrilineal relationships among modern human populations. However, there has been no systematic, worldwide survey of sequence variat...
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