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Article

Isolation of two distinct type I angiotensin II receptor genes.

Biochemical and biophysical research communications - 30 Apr 1992

Elton T S, Stephan C C, Taylor G R, Kimball M G, Martin M M, Durand J N, Oparil S

Abstract excerpt

A rat genomic Southern blot, probed with a type I angiotensin II receptor probe, demonstrated that two highly homologous type I angiotensin II receptors were present. A rat genomic library was subsequently screened and four clones were isolated. From restriction mapping, differential hybridization, polymerase chain reaction amplification and sequence analyses we have determined that there are two unique type I...

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PMID: 1575725
DOI: 10.1016/0006-291x(92)90700-u

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