Article
Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1995
Koike G, Winer E S, Horiuchi M, Brown D M, Szpirer C, Dzau V J, Jacob H J
Abstract excerpt
The renin-angiotensin system plays an important role in blood pressure homeostasis, but the contribution of the type 2 angiotensin II receptor (AT2R) is still unclear. The reports that the AT2R gene has been mapped to the X chromosome in human and rat and the previous report of a gene, Bp3, on the X chromosome responsible for an increase in blood pressure have suggested that the rat AT2R gene (Agtr2) could be...
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