Article
Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression.
Biochemical and biophysical research communications - 15 Mar 1994
Konishi H, Kuroda S, Inada Y, Fujisawa Y
Abstract excerpt
Angiotensin II (AII) plays a major role in regulation of cardiovascular function and fluid homeostasis through the action of an AII type 1 receptor (AT1R). The cDNA encoding a novel subtype of human AT1R (AT1bR) was cloned from a human placental cDNA library. The full-length cDNA clone (1563 bp) encoded a polypeptide that consists of 359 amino acid (aa) residues with 97.2% aa identity to the human AT1aR. All the...
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