Article
Aberrant expression of HOX genes in human invasive breast carcinoma.
Oncology reports - 1 Apr 2005
Makiyama Kokonoe, Hamada Jun-Ichi, Takada Minoru, Murakawa Katsuhiko, Takahashi Yoko, Tada Mitsuhiro, Tamoto Eiji, Shindo Gaku, Matsunaga Akihiro, Teramoto Ken-Ichi, Komuro Kazuteru, Kondo Satoshi, Katoh Hiroyuki, Koike Takao, Moriuchi Tetsuya
Abstract excerpt
HOX genes are known not only as master genes that control the morphogenesis, but also as regulator genes that maintain tissue or organ specificity in the adult body. We hypothesized that dysregulated expression of HOX genes was associated with tumor development and malignant progression such as invasion and metastasis. In this study, we analyzed the expression patterns of 39 HOX genes in human invasive ductal...
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