Article
Homeobox A11 hypermethylation indicates unfavorable prognosis in breast cancer.
Oncotarget - 7 Feb 2017
Xia Bingshu, Shan Ming, Wang Ji, Zhong Zhenbin, Geng Jingshu, He Xiaohui, Vu Tung, Zhang Dekai, Pang Da
Abstract excerpt
Homeobox A11 (HOXA11) is one of the hypermethylated genes in breast cancer and its function in breast tumorigenesis remains elusive. In this study, we analyzed the methylation status of HOXA11 in 264 paired breast cancer and normal tissue as well as in matched serum samples by MethyLight assay. Further, the function of HOXA11 in breast tumorigenesis was analyzed by cell proliferation and migration assays. We...
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