Article
The R72P P53 mutation is associated with familial breast cancer in Jewish women.
British journal of cancer - 28 Mar 2005
Ohayon T, Gershoni-Baruch R, Papa M Z, Distelman Menachem T, Eisenberg Barzilai S, Friedman E
Abstract excerpt
BRCA1/BRCA2 mutations account for a substantial proportion of familial breast cancer, but clearly mutations in additional genes exist, one candidate being the p53 gene. To evaluate its putative involvement in inherited predisposition to breast/ovarian cancer in Jewish high-risk women, mutational analysis of the p53 gene (exons 4-9) was carried out using exon-specific polymerase chain reaction followed by...
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