Article
Characterization of a naturally-occurring polymorphism in the UHR-1 gene encoding the putative rat prolactin-releasing peptide receptor.
Peptides - 1 Apr 2005
Ellacott Kate L J, Donald Emma L, Clarkson Paul, Morten John, Masters Dave, Brennand John, Luckman Simon M
Abstract excerpt
The rat orphan receptor UHR-1 and its human orthologue, GPR10, were first isolated in 1995. The ligand for this receptor, prolactin-releasing peptide (PrRP), was identified in 1998 by reverse pharmacology and has subsequently been implicated in a number of physiological processes. As supported by its localization and regulation in the hypothalamus and brainstem, we have shown previously that PrRP is involved in...
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