Article
Early virological failure with a combination of tenofovir, didanosine and efavirenz.
Antiviral therapy - 1 Jan 2005
Podzamczer Daniel, Ferrer Elena, Gatell Josep Maria, Niubo Jordi, Dalmau David, Leon Agathe, Knobel Hernando, Polo Carolina, Iniguez Daniel, Ruiz Isaac
Abstract excerpt
OBJECTIVE: To describe the occurrence of a high early virological failure (VF) rate and development of resistance mutations in antiretroviral-naive patients receiving tenofovir, didanosine and efavirenz. METHODS: HIV-infected antiretroviral-naive patients with viral load > or =30 000 copies/ml were enrolled in a pilot randomized trial of tenofovir/didanosine (250 mg)/ efavirenz with (arm A) or without (arm B)...
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