Article
Study of HLA segregation in 479 thalassemic families.
Tissue antigens - 1 Feb 1992
Contu L, Arras M, Mulargia M, La Nasa G, Carcassi C, Leone A L, Ledda A, Goddi F
Abstract excerpt
479 families, each with a proband affected by homozygous beta-thalassemia, were typed for HLA. 224 families with a total of 1020 members were typed for the HLA-A, B, C, DR and DQ loci and 255 families with 1046 family members, were typed for the HLA-A, B, and C loci. Altogether, 896 A, B, C, DR and DQ haplotypes and 1020 A, B and C haplotypes were defined. At the same time, 120 healthy unrelated individuals from...
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