Article
The thalassemia syndromes: molecular characterization in the Spanish population.
Hemoglobin - 1 Aug 2001
Villegas A, Ropero P, González F A, Anguita E, Espinós D
Abstract excerpt
This work compiles the results of our research on alpha- and beta-thalassemias, and includes a literature review of the molecular genetics of alpha- and beta-thalassemias in Spain. We studied 1,564 subjects with thalassemia (294 with beta-thalassemia and 1,264 with alpha-thalassemia) by molecular biology techniques. In relation to beta-thalassemia, a total of 15 different mutations were characterized in a study...
Topics
- Alleles
- DNA Mutational Analysis
- Humans
- Mutation
- Spain
- Syndrome
- Thalassemia
- Topography, Medical
- alpha-Thalassemia
- beta-Thalassemia