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Article

Association of the CD14 Gene Polymorphism C-159T with Allergic Rhinitis

1 Jan 2010

Abstract excerpt

BACKGROUND: Altered expression of the cluster differentiation antigen, CD14, may affect the proportion of T-helper type 1 (Th1) to Th2 cells, thereby influencing the immunoglobulin E (IgE) response and associated inflammatory phenotype in allergic conditions. Therefore, the gene encoding CD14 is considered as a positional candidate gene for atopy. Recently, a functional C-159 T polymorphism has been described in...

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PMID: 20109306
DOI: 10.2500/ajra.2010.24.3411

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