Article
Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America - 8 Mar 2005
Song Moon Jung, Hwang Seungmin, Wong Wendy H, Wu Ting-Ting, Lee Sangmi, Liao Hsiang-I, Sun Ren
Abstract excerpt
Gamma-herpesviruses, Epstein-Barr virus, and Kaposi's sarcoma-associated herpesvirus are important human pathogens, because they are involved in tumor development. Murine gamma-herpesvirus-68 (MHV-68 or gammaHV-68) has emerged as a small animal model system for the study of gamma-herpesvirus pathogenesis and host-virus interactions. To identify the genes required for viral replication in vitro and in vivo, we...
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