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Article

The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes.

Biochemistry - 8 Mar 2005

Trieber Catharine A, Douglas Jennifer L, Afara Michael, Young Howard S

Abstract excerpt

Reconstitution into proteoliposomes is a powerful method for studying calcium transport in a chemically pure membrane environment. By use of this approach, we have studied the regulation of Ca(2+)-ATPase by phospholamban (PLB) as a function of calcium concentration and PLB mutation. Co-reconstitution of PLB and Ca(2+)-ATPase revealed the expected effects of PLB on the apparent calcium affinity of Ca(2+)-ATPase...

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Identifiers

PMID: 15736939
DOI: 10.1021/bi047878d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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