Article
Phenotypic analysis of bovine chondrocytes cultured in 3D collagen sponges: effect of serum substitutes.
Cell and tissue banking - 1 Jan 2005
Yates Karen E, Allemann Florin, Glowacki Julie
Abstract excerpt
Repair of damaged cartilage usually requires replacement tissue or substitute material. Tissue engineering is a promising means to produce replacement cartilage from autologous or allogeneic cell sources. Scaffolds provide a three-dimensional (3D) structure that is essential for chondrocyte function and synthesis of cartilage-specific matrix proteins (collagen type II, aggrecan) and sulfated proteoglycans. In...
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