Radiobiological Basis of Low-Dose Irradiation in Prevention and Therapy of Cancer

doi:10.2203/dose-response.06-112.pollycove

Article

Radiobiological Basis of Low-Dose Irradiation in Prevention and Therapy of Cancer

1 Jan 2007

Abstract excerpt

Antimutagenic DNA damage-control is the central component of the homeostatic control essential for survival. Over eons of time, this complex DNA damage-control system evolved to control the vast number of DNA alterations produced by reactive oxygen species (ROS), generated principally by leakage of free radicals from mitochondrial metabolism of oxygen. Aging, mortality and cancer mortality are generally accepted...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.