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Article

Ly6 family member C4.4A binds laminins 1 and 5, associates with galectin-3 and supports cell migration.

International journal of cancer - 10 Jul 2005

Paret Claudia, Bourouba Mehdi, Beer Alexander, Miyazaki Kaoru, Schnölzer Martina, Fiedler Sabine, Zöller Margot

Abstract excerpt

C4.4A is a member of the Ly6 family, with low homology to uPAR. It has been detected mainly on metastasizing carcinoma cells and proposed to be involved in wound healing. So far, C4.4A has been observed as an orphan receptor, and its functional activity has not been explored. Using recombinant rat C4.4A (rrC4.4A) made in a eukaryotic expression system, we demonstrate by immunohistology that C4.4A ligands are...

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Identifiers

PMID: 15729693
DOI: 10.1002/ijc.20977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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