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Nephronectin as a Matrix Effector in Cancer

25 Feb 2021

Abstract excerpt

The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five N-terminal epidermal growth factor-like domains, a linker region harbouring two integrin-binding motifs (RGD and LFEIFEIER), and a C-terminal MAM domain. In this review, we look into the...

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PMID: 33668838
DOI: 10.3390/cancers13050959

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