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Article

Mutational analysis of metronidazole resistance in Helicobacter pylori.

Antimicrobial agents and chemotherapy - 1 Mar 2005

Moore Jill M, Salama Nina R

Abstract excerpt

Metronidazole is one of a few antibiotics effective in eliminating Helicobacter pylori infection of the human stomach. Several chromosomal loci have been implicated in resistance to this drug. Saturation transposon mutagenesis of the H. pylori genome revealed inactivation of the rdxA gene as uniquely able to confer metronidazole resistance.

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Identifiers

PMID: 15728938
DOI: 10.1128/AAC.49.3.1236-1237.2005
PMCID: PMC549284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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