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Article

Search for novel candidate mutations for metronidazole resistance in Helicobacter pylori using next-generation sequencing.

Antimicrobial agents and chemotherapy - 1 Apr 2015

Binh Tran Thanh, Suzuki Rumiko, Trang Tran Thi Huyen, Kwon Dong Hyeon, Yamaoka Yoshio

Abstract excerpt

Metronidazole resistance is a key factor associated with Helicobacter pylori treatment failure. Although this resistance is mainly associated with mutations in the rdxA and frxA genes, the question of whether metronidazole resistance is caused by the inactivation of frxA alone is still debated. F...

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Identifiers

PMID: 25645832
DOI: 10.1128/AAC.04852-14
PMCID: PMC4356779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25645832-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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