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Article

pitx3 defines an equivalence domain for lens and anterior pituitary placode.

Development (Cambridge, England) - 1 Apr 2005

Dutta Sunit, Dietrich Jens-Erik, Aspöck Gudrun, Burdine Rebecca D, Schier Alexander, Westerfield Monte, Varga Zoltán M

Abstract excerpt

Hedgehog signaling is required for formation and patterning of the anterior pituitary gland. However, the role of Hedgehog in pituitary precursor cell specification and subsequent placode formation is not well understood. We analyzed pituitary precursor cell lineages and find that pitx3 and distal-less3b (dlx3b) expression domains define lens and pituitary precursor positions. We show that pitx3 is required for...

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Share to Pituitary Gland, Anterior
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15728669
DOI: 10.1242/dev.01723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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