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Article

The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum.

Blood - 15 Jun 2005

Tiffert Teresa, Lew Virgilio L, Ginsburg Hagai, Krugliak Miriam, Croisille Laure, Mohandas Narla

Abstract excerpt

In most inherited red blood cell (RBC) disorders with high gene frequencies in malaria-endemic regions, the distribution of RBC hydration states is much wider than normal. The relationship between the hydration state of circulating RBCs and protection against severe falciparum malaria remains unexplored. The present investigation was prompted by a casual observation suggesting that falciparum merozoites were...

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Identifiers

PMID: 15728121
DOI: 10.1182/blood-2004-12-4948
PMCID: PMC1894996

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