Article
Excess hemoglobin digestion and the osmotic stability ofPlasmodium falciparum–infected red blood cells
5 May 2003
Abstract excerpt
During their asexual reproduction cycle (about 48 hours) in human red cells, Plasmodium falciparum parasites consume most of the host cell hemoglobin, far more than they require for protein biosynthesis. They also induce a large increase in the permeability of the host cell plasma membrane to allow for an increased traffic of nutrients and waste products. Why do the parasites digest hemoglobin in such excess? And...
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